This mission starts immediately after finding Lisa in It's Not Safe Here. This is an escort mission and thankfully, Lisa isn’t controlled by a dumb AI. She will actively stay away from danger and find ways to hide. That said, you only need to worry about yourself. However, you should remain close to Lisa since the mission will fail if you leave her behind.
This time, you have to escort Lisa back to your Bike. The town is now filled with freakers. You don’t need to actively kill all freakers you encounter; you need to prioritize avoiding them and killing only those that block your path. Make sure to scout using your Binoculars before moving ahead. Mark enemies as well so you can track their movement.
Move behind the buildings since most freakers are found along the main road. Keep an eye on your Radar and always pick off lone freakers within your range. I suggest walking around behind the gas station so that you can use the ladder outside to reach its rooftop where there are enough materials to craft molotovs. Take out the two newts on the rooftop and you’ll have your own safe space.
There’s a bear guarding your Bike so lobbing molotovs at it and slowly burning it to death from the rooftop is the easiest and safest way to deal with it. Don’t worry about Lisa since she’ll hide inside the dumpster beside the building.
You may need several molotovs to kill the bear. After it goes down, collect the loot nearby and ride your Bike. During this mission, your bike will require no gas and will take no damage. Once Lisa settles in, follow the GPS track and ride out of town.
Once you reach the tunnel, you’ll encounter a marauder blockade. Get off the Motorcycle and take cover. Take out all enemies so you can continue. Loot the bodies and collecting other items then return to your Bike.
From hereon, it’s just a straightforward ride to Hot Springs. Deliver Lisa there and the mission will be complete.