After the district falls back to Vito's hand, he'll ask you to check with his lieutenant, Alma and see what you can do to help. Head to the contraband warehouse and talk to her.
Your objective is to head to the marked location after accepting the job from Alma, clear the area and steal the truck. You won’t have any pursuers so you can just drive at your own leisure until you reach the contraband warehouse safely. Take note that while transporting the goods back to Alma, Marcano's hitmen may hit. If that's the case, find a good area to stand your ground and call in your own hit squad. It will be impossible to lose them with the trailer truck so might as well engage them in a shootout and get them off your back for a while.
Completing two runs will increase Vito’s earn to $100,000, unlocking the Mob Doc: Add Another Adrenaline Shot and also increasing your kickback to $2000. The game will also notify you that the earn for all rackets for the Vito's operations is already at max; you can do more of these runs when you assign more rackets to the Vito..