When you first begin the game, you will only have access to Normal Mode Difficulty; however, there are actually two additional Mode Difficulties that can be unlocked. The second Difficulty Level is known as Hard Mode, while the third is called Fusion Mode. In order to unlock Fusion Mode, you must first defeat Story Mode once time through. But that's not all! You must also have a special Samus Amiibo, available for purchase online, to access this exclusive Difficulty Level. But be warned: Fusion Mode causes Enemies to do four times the amount of damage than in Normal Mode.