Your Account
    Log into your account here:
       Forgot Password

    Not registered? Sign Up for free
    Registration allows you to keep track of all your content and comments, save bookmarks, and post in all our forums.


Thank you for printing this page from Remember to come back to check for updates to this guide and much more content for The Binding of Isaac Rebirth

Pills are one-time-use items that are (obviously) in the form of medicine in-game. The pills come in a range of colors and the effects of the pills will change each playthrough. If you pick up a pill and are brave enough to use it, you will be instantly informed of what you have done to yourself and the pill will be named each time you pick it up for that play through.

Trinkets affecting pills- Safety Cap

Items affecting pills- PhD

Very Helpful
Not Useful

Anything missing from this guide?
ASK A QUESTION for The Binding of Isaac Rebirth


Comments for Basics

Add a comment

Please log in above or sign up for free to post comments
No comments yet. Tell us what you think to be the first.
Click to close