#2 High Brow

Challenge: #2 High Brow

Description: The High Brow challenge requires you to run to the Depths II and defeat Mom.

Unlock: This Challenge is unlocked by default.

Starting Items:

Butt Bombs

E-Coli

Flush

Number One

Petrified Poop

Strategy: Number One is vastly improved over the original BOI game. Your range is still diminished greatly, but the damage is still there. Seeing as your Tear Rate is increased, it would be beneficial to find items that have a percentage to prok based on when you shoot tears. Such as Blood Clot, Infestation or The Common Cold. You will find yourself being in closer proximity to enemies in order to damage them, so finding an orbital or two would come in handy. Making the Guppy is always recommended, but since you will be starting with such a high Tear Rate, you will be spawning flies just as fast. Items that require a charge time also benefit from your fire rate, such as Brimstone or Monstro’s Lung. Lastly you should be on the lookout for items that increase your range as soon as possible in order for you to establish more distance between you and the enemies.

Completion: Completion of this challenge unlocks the Rune of Jera.