18 :: The Destroyer - Devil May Cry 4
This mission is just one big boss fight. Your objective; take down the colossal Savior! Now, this is no simple task, even for one as well-versed in combat as Dante. You obtain the Yamato at the start of this mission. With this artifact in your possession, the Dark Slayer combat style can be toggled by attempting to switch to the talent you currently have selected. This weapon won't be of much use during this battle, but it may come in handy during subsequent playthroughs.
The key to bringing this guy down lies in destroying the crystals on its forehead, wrists, shoulders, shins and back. This battle can be somewhat confusing, as you'll have to use the blue seals to reach the different platforms around the Savior, so it's easy to lose your place. Of course, the Savior won't just stand idly by while you work to destroy the weak points; it'll throw plenty of attacks your way, most of which are quite damaging.
The Savior will likely send three dark orbs your way at the start of the battle. Destroying one of these orbs yields White Orbs that, when collected, will restore some of your D.T. Gauge, so blast just one of them with the shotgun, then Side Roll, jump, or Dash out of the way to avoid taking damage.
First things first, getting off of the starting platform. Hop onto the blue seal to reach a lower platform. Two knights spawn down here; you don't want to waste too much time with these guys, so flip on Devil Trigger and take them out with a few quick Stingers, or sit back and hope the Savior kills them for you. Putting yourself on the lower platform poses significant danger, though, as the Savior can now reach you with its fists.
You're in prime position to take out two of the Savior's weak spots, though. Wait until it's about to hit you with its left hand (dodge fist slams from its right hand) and avoid the slap, then jump onto the back of its hand. Don't jump at all once you're on its hand and it should pull you inwards. Be careful while you're on its hand, though, as the Savior will occasionally conjure dark orbs and launch them towards you once in awhile. Jump just before an orb is about to hit, or use Jealousy Pandora to stop it. You'll have jump to avoid the swipes from its right hand, too; get ready to jump when you see it raising its right arm.
Left Wrist and Shoulder
From here on out, it's impossible to know exactly where the blue seals are going to take you. Basically what you want to do here is get yourself onto a platform that is close enough to the Savior's weak spot or onto a platform where it can perform certain attacks. To take out the forehead crystal, you'll need to get onto its left hand again. Once on a platform where the Savior fist slams and slaps its left hand down, jump onto its hand, wait to be pulled closer, then lock-on and use Jealousy Pandora to shatter the crystal.
In order to destroy the crystals on its back, right shoulder and right wrist, you must land on a platform with a stun gun on it. When you land on one of these, immediately start pummeling the wheel with attacks and activate it before the Savior can knock you down from the platform. The gun shoots out a couple of orbs that will temporarily incapacitate the colossus.
It can be hard to know if you're on a platform that is suitable for hitting the shin crystals. Likely the Savior will do nothing but launch dark orbs and occasionally round-up, gather energy and throw a single giant orb towards you. Try to lock-on with Pandora and use Jealousy; if the style meter indicates that you're dealing damage, it's a good platform. So all you really need to do then, is jump up and Air Hike into the air and hit the shin crystals with Jealousy Pandora until they're both shattered.
Once all but the Savior's chest crystal remains, it will begin to charge and eventually fire a gigantic laser beam at your platform. To avoid taking a large amount of damage, simply use the blue seals to leap from platform to platform. You're toast if you get caught in the beam, so keep an eye out for the Savior's charging phase (it's hard to miss). Use the blue seals to leap to other platforms until the Savior's health bar appears at the bottom of the screen.