This is your first mission for Gianna. She needs help with her career, struggling as a woman in the DICS club. She needs a big case but there's nothing going on in the crime world (apparently), so we need to create something for her. The Syndicate is moving some weed out of a warehouse but Gianna has planted loads of heroine there. It will go from a small crime to a huge headline-maker for her, as long as we can get the police involved.
Head to the Syndicate HQ to get started. You may find that the Syndicate soldiers all around their HQ will be hostile to you. If that's the case, you'll have to clear the surrounding area first, so you might want to stock up on weapons and medkits before you begin. Once you've got a path to the blue arrow, activate it. You now need to battle your way in to the back of the warehouse. You can stick to the sides, climbing over objects and using cover, or you can barrel your way in.
Head to the back of the warehouse and get in the car
Once you reach the back, get in the car. We need to get some police attention on it (2 shields' worth), so head back into the center of the city and run over some pedestrians. To get two stars of attention, you really have to fire on or run over a police officer. Once you've achieved this, return to the Syndicate HQ to give the car back. You then need to get out and run away within 30 seconds. If there is another car nearby, get in and drive away. If not, running will suffice. Once the timer has reached zero, the police will turn up, discover the 'hot' car, and the mission will end.