Takeover the City
Head to the marked location to start this mission. Next, head to the next location to find a sex doll. (This counts towards the 20 total number of dolls you can find in the city)
After getting the doll, head to the gang operation next. Head there and take out all marked targets to destroy the operation and for you to take control of the area. Head to the next location and do the same thing.
If you don't know yet, you can also gain notoriety from rival gangs just like the police. To remove the notoriety, hide in your safe house or any owned store. For this mission, head to the marked Friendly Fire branch and stay there to complete the mission.