You have to play a "game" a couple of times throughout the story, where you have to roll a die (single dice). Stand by it and watch the order that the numbers go in. Whatever number is on top when you hit it is what number it will land on(9/10 times). So learn the order, and I recommend using buster to hit it because it seems to be a little faster. ALSO, if you didn't already know: Blue spaces are rewards, white spaces are nothing, yellow spaces send you forwards or backwards, and red spaces are fighting. You can make it completely through a "game" without having to fight, just getting easy blood orbs!!! Hope this helps someone! Gimme a thumbs up PLEASE!
On mission 14 there will be a new enemy. They will try to grab you and take you under the floor. Simply jump forward as the blue star appears then do a double stinger on the CLOSED enemy. Then it will give you two BIG green orbs which should bring your health up to half way. Do this as many times as you wish.
When you have beaten 'Devil May Cry 4' you'll be able to view the first part of the secret ending which features Dante, Trish and Lady before the credits begin. If you want to view the second part of the ending you must protect Kyrie from being hit for 90 seconds during the end credits battle. If Kyrie is hit during this time the credits will end and you won't see the second part of the ending.