This great cheat which will help you progress through the game without worrying about how much 'Life' you have remaining is entered at the 'Main' screen by pressing Circle, L2, X, Square, Triangle, R2, L2.

When the main story has been completed this empathic sight which enables you to see hidden messages and tell friend from foe can be used whenever you want regardless of the synchronization levels of the Animus machine.

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It is a complete walkthrough of the game with screenshots.

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Assassin's Creed Wallpaper

Before the Master can take away your radar ability making it difficult to see try and lock on to him and use your throwing knife. Doing this will stop him from being able to use his power to blind you which makes it easier for you to kill him as you'll be able to see him.

Kill Anyone without Losing a Life:
When you have beaten the Game you can replay Memory Blocks in Story mode and can kill anyone you like without being penalised.

Unlock Secret Ending:
When you have beaten the game and the credits have completed you will be able to view a secret ending.

Loud Assassination:
Hold LB + RB and press X to perform this type of assassination which can be used when approaching a guard, the only problem is that because it's noisy it will alert other guards.

Silent Assassination:
Hold LB and press X to perform this type of assassination which is most effective when used from behind a guard as nobody will hear a thing.