Neutral
Civilians roam the streets and generally keep out of your way. Most will react to your presence and will run away if you approach with your weapon raised. A few civilians will highlight as being in need and if you do not show aggression they will approach you and request help.
The item they need will be shown and you have the option to give it to them. This is normally medkits, food or Water supplies that you may have found in backpacks and containers around the city. If you give the item to the civilian then you will be rewarded with a random level gear item.
Some civilians are also found as hostages in Encounters with Street gangs. When you release them don't expect any thing other than a thank you from them. But do check the room they were held in as there is generally a box with a loot item in it.