Unlock Switch Hero Option:
Successfully complete ALL story mode missions to unlock the 'Switch Hero' option at the 'Pause' menu.

Unlock Venom Races:
Successfully complete ALL Story mode missions.

Unlock Medium Combat Tour Difficulty:
Successfully complete 8 easy Combat Tours after 'Hell of a Mess' (Chapter 4).

Unlock Medium City Event Difficulty:
Successfully complete 'Inexpugnable' (Chapter 6) and 10 City events.

Unlock Hard City Event Difficulty:
Successfully complete 'Class Trip' (Chapter 8) and 20 City events.

Unlock Hard Combat Tour Difficulty:
Successfully complete 12 Medium difficulty Combat Tours.

Unlock Insane Combat Tour Difficulty:
Successfully complete ALL Hard difficulty Combat Tours.

Pause game-play and go to the 'Set-up' menu and enter the following codes

All Landmarks:
Up, Right, Down, Left, Down, Up, Right, Left

All Concept Art:
Down, Down, Down, Up, Down, Up, Left, Left

All Comics:
Left, Left, Right, Left, Up, Left, Left, Down

All Characters:
Right, Down, Right, Down, Left, Up, Left, Right

Unlock Medium City Event Difficulty:
Complete 10 City Events and also Complete Chapter 6 'Inexpugnable'.

Unlock Hard City Event Difficulty:
Complete 20 City Events and also Complete Chapter 8 'Class Trip'. Unlock Higher Combat Tour Difficulty Levels and get Health Bonuses

Health Bonus and Medium Difficulty Combat Tours:
Complete 8 'Easy' difficulty Combat Tours After Chapter 4 'Hell of a Mess'.

Health Bonus and Hard Difficulty Combat Tours:
Complete 12 'Medium' difficulty Combat Tours.

Insane Difficulty Combat Tours:
Complete all 'Hard' difficulty Combat Tours. Unlock Extras

Switch Hero Option on Pause Menu:
Complete all Story Missions

Venom Races:
Complete all Story Missions

Spidey Wrestling:
Complete 30 City Events and Collect 30 Tokens.

Parker Hoodie:
Complete 32 Combat Tours and 75 City Events and Collect 75 Tokens.

Arachnoman:
Complete 48 Combat Tours and 90 City Events and Collect 90 Tokens.

Peter Parker:
Complete 50 City Events and Collect 50 Tokens and also Win the 4th Race against Johnny Storm.

Symbiote Spider-Man (Black Costume):
Complete ALL Combat Tours and 100 City Events and get ALL Tokens.