Complete the Rebirth Ending, then load it on the load menu on the main menu then play it again. When you get to the part where you meet Maria for the first time, head across from the plark to a empty lot and you'll see a dog house. You get the key there.
Towards the end of the game, right after you watch the tape, head to the examination room to use the key there. Enter the room.
To get this valuable weapon you have to beat the game on the same save file twice. Then on your third play through, when you go to the motorhome, there will be a can sitting on the table. Grab it to get the Hyper Spray. Different colours depend on your stars after each completed game.
Remember Maria? Well in one part James and Maria are in a tunnel like area being chased by the pryamid head guy! At the end of that tunnel is a elevator!(safe area) Maria is slow so push her in because she knows a answer to a riddle (face puzzle) with out her YOU CAN'T SOLVE IT
1. First, examine the toilet, in the same room the safe is in, for a wallet
2. Second, inside the wallet you should see a safe combo
3. Third, you should get your own combo, mine was 13>>10<<19>>20
4. Fourth, Write Down your combo on a paper, be sure you add an extra << at the end of the last number, be sure you write the directions opposite the directions on the wallet
5. Fifth, Now you should have something that looks like this 13<<10>>19<<20>>
6. Sixth, you should first start off on a random number, then turn left until you land on 13, right until you land on 10, left until you land on 19, and right until you land on 20, then the safe should open up with 30 handgun bullets
Apartment Pyramid head
When you get locked in the stairway with Pyramid head, keep moving so he can't hit you, don't try killing him cause he won't die, after 3 or 4 minutes he will leave
After you meet Maria, don't bother walking all the way to the end of the road, instead just walk into Pete's Bowl-O-Rama