Avoid Death:
When you are about to die press 'Esc' then save and exit the game. When you reload, your game you will be at the starting location.

Quick Restore:
When you are near death save and exit the game making sure you are in Rouge's Encampment. Then, talk to Akara and she will give you full life and full mana.

Retrieve Items after Death:
When you have died save and exit the game. Then restart the game and your corpse will be in town allowing you to retrieve your possessions.

Better shield defense:
Raise your shields defense by putting perfect amethysts in it. For example, getting an ancient shield with three perfect amethysts will add 86 to the defense.

Avoid Dying from Poison:
If you are about to die when poisoned, quickly make a town portal and go through. You cannot die in town. This also works with hirelings.