Master Ball: who to use it on
Don't use your Master Ball on Mewtwo or the legendary birds (you can use Timer Balls or Ultra Balls on them). You can get Timer Balls at the Two Island mart after you beat the elite four. Save your Master Ball, and use it on the legndary dog (Entei, Raikou, or Suicune) that apears in your game after you beat the elite four. This is important, because the Master Ball catches the Pokemon without fail, and these Pokemon try and run away as soon as you see them.
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