What is the best way to clear a room?

Siren Grenades are fairly overpowered and just use one, or two at most, to clear any room with more than two enemies.

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If you don’t want to use too many items.

1. Supersense - know your enemies.
2. Stealth - kill listeners first, engineers can easily be lured out if needed or you can stealth‘em.
3. Brute force - Berserkers take 3 shots to kill with a harvester, if your porting recharges fast you can let them get in the swinging motion, then port behind them and use the harvester. For weeper get a quality shield and take the blast head on then beat the weeper with the harvester while it is recharging.
4. You don’t need to kill’em all - avoid sentry guns if possible, or use items (Knife or gun).
5. Items - For the bloodhound just use the ivy serum it will save you much pain (they 1 hit KO enemies, if you ivy 2 bloodhounds one will murder the other).