#1 - Lightning
Lightning is over five hundred years old and is the keeper of all the human souls. She first appears as the protagonist in Final Fantasy XIII, in which she features as a resident of the artificial world of Cocoon. After her sister Serah is declared an enemy of Cocoon, Lightning attempts to save her. She and others are then chosen by the fal'Cie, a divided race of demigods who rule the worlds of Gran Pulse and Cocoon, to destroy Cocoon.
#2 - Exdeath
Exdeath is the main antagonist from Final Fantasy V. He is an immensely powerful, competent, manipulative, and demonic being born from all of the evil souls sealed inside a great magical tree, who manifests as an imposing knight clad in holy-looking armour. His alternate form is Neo Exdeath.
#3 - Ultimecia
Ultimecia is the main antagonist from Fantasy VIII. She is a powerful sorceress from the future who seeks to compress time and fuse past, present and future into one single moment, extinguishing all existence but her own. She sends her spirit to the game’s protagonists' time and possesses the sorceress Edea Kramer. Squall Leonhart and his friends manage to track her down to her own Era and defeat her.
#4 - Cloud of Darkness
The Cloud of Darkness is the main antagonist of Final Fantasy III and its goal is to cause a flood of darkness to reduce the world to nothingness. Cloud of Darkness appears as a green-skinned female humanoid emerging from a portal of darkness at its waist. It has a red heart-shaped mark on its forehead, and several mouthed tentacles around it.
#5 - Kefka
Kefka is the main antagonist of Final Fantasy VI who is an insane, egomaniacal mage from another world where magic and espers once lived who has acquired godlike powers. Even though his mind was irreparably damaged by an infusion of artificial magic his emperor still places a great deal of trust in this madman. Fellow soldiers in the Gestahlian Army hate and fear Kefka for his madness and cruelty.