Unlock New Challenges
Complete the following tasks to unlock the corresponding Challenge. When you then complete the Challenge you will unlock rewards that will generate in subsequent games (Challenges 1-3 and 12-18 are available at the beginning).
Challenge 4 - Darkness Falls:
Defeat Mom's Heart a total of 11 times
Challenge 5 - The Tank:
Possess a total of 7 Red Heart Containers at any point during a run (unlocks Magdalene)
Challenge 6 - Solar System:
Defeat Mom's Heart a total of 3 times
Challenge 7 - Suicide King:
Defeat Mom's Heart a total of 11 times
Challenge 8 - Cat Got Your Tongue:
Collect 3 Guppy Items during a single run (Become Guppy)
Challenge 9 - Demo Man:
Defeat Mom's Heart a total of 9 times
Challenge 10 - Cursed!:
Possess a total of 7 Red Heart Containers at any point during a run (unlocks Magdalene)
Challenge 11 - Glass Cannon:
Defeat Loki once and clear The Family Man challenge
Challenge 19 - The Family Man:
Collect both Key pieces from the Angels in a single run
Challenge 20 - Purist:
Defeat Mom for the first time
Challenge 21 - XXXXXXXXL:
Defeat Mom for the first time
Challenge 22 - SPEED!:
Defeat Mom for the first time
Challenge 23 - Blue Bomber:
Defeat Mom's Heart a total of 11 times AND destroy at least 10 tinted rocks
Challenge 24 - PAY TO PLAY:
Defeat Issac as Cain
Challenge 25 - Have a Heart:
Defeat Mom for the first time
Challenge 26 - I RULE!:
Defeat either The Lamb or ??? At least once
Challenge 27 - BRAINS!:
Defeat Issac a total of 5 times
Challenge 28 - PRIDE DAY!:
Defeat Mom for the first time
Challenge 29 - Onan's Streak:
Defeat Satan while playing as Judas
Challenge 30 - The Guardian:
Defeat Mom for the first time
Challenge 31 - Backasswards:
Defeat either The Lamb or ??? At least once
Challenge 32 - April Fools!:
Defeat Mom for the first time
Challenge 33 - Pokey Mans:
Defeat Mom's Heart a total of 11 times
Challenge 34 - Ultra Hard:
Defeat either The Lamb or ??? At least once
Challenge 35 - Pong:
Defeat Issac a total of 5 times
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