This Time at the Pub the mission will start after sleeping and speaking to the Admiral.
Go into the sewers for the main quest and investigate markers. Just remember there are TWO Runes
here as well.
Go to marker and kill the two weepers. Then pick up the note nearby. Take out the heart for assiting you finding the TWO nearby Runes
Then leave Via the chain in the other room in the sewers.
Head back to the bar and talk to the Admiral again.
He will tell you we have to take out the Pendleton Brothers. Go to Samuel take boat to the distellry district.
Once there, the game takes several options for completing side quests. Please see the rune section, for information on gathering all the Runes
. As well check out ALL sections as neccessary.
Basically all you have to do really is go to golden cat via marker and kill the two brothers by both following markers. You will also have to free and escape with Emily.
That is it for this part of the quest, the hard parts come within the meat of this guide in the other contents. Read them you will find quite a bit of information.