There are 45 achievements for Ben 10 Ultimate Alien: Cosmic Destruction.
| Achievements | Award |
|---|
| 10 Hit Combo Get a 10 hit combo | 10 |
| Art of War Discover all of the Combat Bonuses | 10 |
| Better, Faster, Stronger! Fully upgrade one alien | 10 |
| Brawler Defeat 100 enemies | 10 |
| Funny Business Complete the Zombozo Ultimate Event | 10 |
| Power Up! Spend 1000 on upgrades | 10 |
| Savior Save all of the civilians in the Final Battle | 10 |
| Stinky Savior Complete the Sunder Ultimate Event | 10 |
| Stone Cold Defeat the Terracotta General | 10 |
| Ultimate Echo Echo-wned Complete the Ultimate Echo Echo event | 10 |
| E-Knocked Out! Complete the Catacombs level | 15 |
| Eye of the Storm Complete the Final Battle level | 15 |
| Fall of Rome Complete the Colosseum level | 15 |
| Great Walls of Fire Complete the Great Wall level | 15 |
| Hunter Has Become the Hunted Complete the Devil's Tower level | 15 |
| Pwned the Clones Complete the Amazon level | 15 |
| Rescued at What Cost? Complete the Tokyo Nights level | 15 |
| Threat Destroy 200 breakable objects | 15 |
| Torn Asunder Complete the Eiffel Tower level | 15 |
| Warrior Defeat 200 enemies | 15 |
| Thanks Watch the entire credits | 20 |
| Ultimatrix Bearer Defeat 50 enemies as Ben Tennyson | 20 |
| 25 Hit Combo Get a 25 hit combo | 25 |
| Camera Shy! Destroy all the security cameras in the Amazon level | 25 |
| Conqueror Defeat 500 enemies | 25 |
| Devils Tower Sumo Slammer! Find all of the hidden Sumo Slammers in Devil's Tower | 25 |
| Eiffel Tower Sumo Slammer! Find all of the hidden Sumo Slammers in the Eiffel Tower | 25 |
| Immobilized Destroy all cars within the game | 25 |
| Investor Spend 10,000 on upgrades | 25 |
| Menace Destroy 500 breakable objects | 25 |
| The Amazon Sumo Slammer! Find all of the hidden Sumo Slammers in the Amazon | 25 |
| The Catacombs Sumo Slammer! Find all of the hidden Sumo Slammers in the Catacombs | 25 |
| The Colosseum Sumo Slammer! Find all of the hidden Sumo Slammers in the Colosseum | 25 |
| The Final Battle Sumo Slammer! Find all of the hidden Sumo Slammers in the Final Battle | 25 |
| The Great Wall Sumo Slammer! Find all of the hidden Sumo Slammers in the Great Wall of China | 25 |
| Tokyo Nights Sumo Slammer! Find all of the hidden Sumo Slammers in Tokyo Nights | 25 |
| Go Ultimate Complete the first Ultimate Event; Defeat all of Vulcanus’ minions. | 5 |
| Vandal Destroy 30 breakable objects | 5 |
| 100 Hit Combo Get a 100 hit combo | 50 |
| 50 Hit Combo Get a 50 hit combo | 50 |
| Deep Pockets Earn One Million DNA | 50 |
| Electric Slameroo! Find all of the hidden Sumo Slammers in the game | 50 |
| To the Moon Complete the Game | 50 |
| Ultimate Aliens Fully upgrade all aliens | 50 |
| You Wanna Fight? Unlock Rath as a playable character | 50 |
