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Due to a somewhat unresolved balance issue, I've found through playing the game you can easily win jsut with a single artillery unit.
For the Atreides, it's the Minotaur.
The Ordos has the Kobra.
And the Harkonnen have their Missile Tanks.
I've found through numerous playthroughs (all on my youtube let's play) that the Minotaur is the most devastating of them all due to having slightly larger ranges than the Kobra, and dealing damage through multiple consecutive hits.