What is the Best Strategy?
The only logical way to play combining games such as these is to systematically combine each material with every other material as soon as it’s discovered. Working through each possible creation and keeping a detailed list ensures that you will eventually, in the fastest way possible, achieve all the creations.
Descriptions
Read the profiles of the new items in the encyclopedia carefully as the discriptions are like little riddles that will give you ideas on what to combine next.
Creative and Clever
Don't worry if you know nothing about science because the game stops being scientific very early on and you will instead have to rely on being creative and clever.
Follow the Line
Always follow the line when you unlock something until an item is 'Final' and it disappears from your workspace.
Getting Hints
You can earn three hints one at a time if you watch a video for each. Remember though that once you have done this you will need to wait 5 hours before the next batch becomes available.
Use Hints Carefully
Open and solve one hint at a time instead of opening all three of them at once. That way as you find new combinations, those new items will increase your inventory and make your other two hints less specific.
Group Items
If you line up a group of three to five items on your workspace and then double tap you will be able to make two of them. Then as you match items and one turns into another new thing you will not have to go back and find it again.