Combinations
Try to get combinations, especially the wrapped candy and the striped candy, and the sprinkle donut hole and the striped candy. Those two are the best combinations and when used together will clear over half the board. Those combinations will also get you to places that are otherwise unreachable. Another useful combination is a wrapped candy switched with another wrapped candy, when used together this combination will ignite a 6 by 4 square which can clear a huge area.
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