After waking up, leave your motel room to get your next objective. You have to use your Profiler to profile the people near your hideout for potential crimes. Use the security cameras to make your work a lot easier instead of walking around. Once you spot a potential suspect, you'll have the option to place a marker to the potential crime location. Head there but get near just enough to hide yourself. Hack the nearest security camera to identify the potential victim or criminal. Make sure you don't get detected. Once you get the ctOS Alert warning, head to the area and intervene. Catching the criminal without killing him gives you a greater reputation reward. After taking down the criminal, you'll earn some EXP as well.
From hereon, you can now explore the city as you please or head to the next campaign mission. After receiving Jordi's call, you'll also unlock Car on Demand activities. While you're in the area, I suggest unlocking the ctOS tower first to unlock various Collectibles, Privacy Invasion points, side Investigations or extra hideouts.