Defeating Otto Destruct - Ratchet And Clank: Size Matters
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To be able to defeat the final boss (Otto Destruct) you have to have four weapons.
1) The Optical Maser Array
2) Electro Rocket (with Shock and Lock-On mods)
3) Shield Barrier
When you have ALL 4 weapons you have to put up a shield and use the Optical Maser Array to lower his shield. Fire the Electro Rockets at him and keep doing this until he is defeated. If you run out of ammunition while you are doing this use the PDA.