Characters.
This game is going to be HUGE, here is a list of some new, and reoccurring characters.
Snake(duh. The reason he's old is because the cloning thing is failing.)
Otacon( still working with snake. This time he can control a robot to help snake during missions.)
Raiden( he's a super ninja who can't feel pain.)
Naomi hunter( she's back in this one as well, She says that snakes has only six months to live)
Roy Campbell( He gives the mission to snake as a hired hit. Snake is to eliminate Liquid. )
EVA( Eva returns as a 78 year old lady who wants snake to call her big mama, and fights against the patriots.)
The patriots, or la-li-lu-le-lo, are a big factor for this game even though in mgs2 it said that they died 100 years ago.
Johnny Sasaki( yes, johnny is in this one as well. He still has diarrhea, but this time he works for Meryl.)
Meryl Silverburgh( She is the leader of the new foxhound unit, and still trying to get snake's approval.)
Mei ling( She is in this one as well, but not sure about the role.)
Revolver ocelot( him, and liquid have fused into one person, liquid ocelot. )
Vamp( it's unknown what role he'll play.)
That's all for now.
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