One setup that I made was for the 1966 Chevelle. Put your VCG to 8. Put your wheelie bars on double. Make them 40 length, 8 inches high, and 85 stiff. Make the LF and LR wiegh 648. Make the RR and LR wiegh 681. Make your transmission a Custon Automatic. 2.70/1.57/1.25/0.77. Your converter should be 4500 stall. Your motor should be a 302 small block ford. 16.00 compression, 850 flow, tunnel ram induction, Canted-rectangular pro stock ports and mods, Small tube headers with open exhaust. The valves should be 2.19/1.90 and the motor a roller motor. Make your fuel 11.00 on gasoline, nitrous. Make your cam shaft a dual purpose street cam. Put your front travel on 5 inches on both and 3 inches on ride height. For the rear, made them both 2 inches. Go to your tires and make your rear tires dragslicks 30.00x 15.00 with 8 pds of air. GO to devices and make your rev. Limiter 3500, 7500, and 13000. Put your dial-in to 8.52 for a base-line. Well, now you are ready to go partner. Let me know if you guys need anything else. :P
You can have the most horsepower but you have to know how to use it.
To get the horsepower: Increase bore and stroke to 7.0, make it have 12 cylinders, 4000 on fuel flow rate, get any super or turbo, and make it powerful, use methanol-nitromethane, use 3.5 and 3 on valve size, use the largest drag slicks , and largest front skinnies, and use 2 psi on all tires. Do all of this on a top fuel car and don't change anything else except to use the ford 4 speed auto at the bottom. From here use small setups on the chassis.
Start by messing with the weights, and the wings. Put them on the lowest, and start working to increse the weight and downforce. Save often, if you mess up you may not fix it. If you tweek right you can run a 4.8 at 325!