If you arefighting with someone that blocks every third time you hit them and they block, instead you can hit them twice then grab them, and if you got the fighting skill submision, do that, if not that grab them then try to push them on the wall or where there are people, they will throw the person then attack.
Hope this would work.
We have more cheats and tips for this game here, Def Jam: Fight for NY cheats
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