To defeat this giant, flying, snake-dragon demoness use Devil Trigger and Roulette Spin on her head. If she turns into a spider, power up and use Buster on her egg sack. If she grasps her forehead in pain use Buster, then tap 'Exceed' to give the attack extra power.
Reel yourself close to Berial's head using the Grim Grip and attack with your sword. When the combos are done use Grim Grip while still in the air and when his flames are gone jump up and grab his head with the Devil Bringer. When he lands use Devil Bringer again to throw and punch him. Now run away a short distance to avoid an explosion he releases in the area around him. Make sure to pick up Green Orbs from the destroyed buildings and roll to avoid his flame geysers and sword attack. Keep attacking using this strategy and remember to use your Charge Shot and you should be able to defeat him in under a minute.
Unlock Secret Ending Featuring Dante, Trish and LadyAdded 23 Jul 2008, ID #12871
Complete the game to view the first part of the ending sequence then during the credits battle mini-game protect Kyrie from being hit for 1 minute 30 seconds. If Kyrie is hit during this time the credits will end and you won't see the second part of the ending.