Fallout 3 Guide
When you've completed the Blood Ties Misc. Quest and have gotten the Hematophagy Perk, these Blood Packs will give you 20 Health instead of 1. This makes them a decent way of healing yourself when the need is high. You can also sell Blood Packs to Vance for 15 Caps a piece.
There are 20 Bobbleheads in the wasteland: They either increase one of your SPECIAL stats by 1 permanently, or one of your Skills by 10 permanently.
Custom Weapon Schematics: (23)
You can create 7 different types of Custom Weapons. In order to do so, you'll need the schematics for each of them. The more schematics you have, the better the quality of your weapon.
Fat Men: (9)
These Mini-Nuke Launchers are semi-rare items, as there are only 9 of them to be found in the entire wasteland.
Mini Nukes: (71)
The Fat Man's ammo is scarce as well, and there are only 71 Mini Nukes scattered over the wasteland.
Scribe Jameson at the Brotherhood Capitol will give you 100 Caps for each Holotag you find. Dead members of the Brotherhood will hold these Holotags.
Nuka-Cola Quantum: (94 )
These blue fluorescent bottles of Nuka-Cola are part of the aptly named Misc. Quest: The Nuka-Cola Challenge. There are 94 of them in fixed locations, but you should always check Nuka-Cola Vending machines because there is a 10% chance you'll find an extra Nuka-Cola Quantum in them.
Pre-War Books: (98)
At the Arlington Public Library you'll find Scribe Yearling. She is trying to save what's left of our intelligent culture by treasuring books that date from before the war. Collect these Pre-War Books and she'll give you 100 Caps per book.
Skill Books: (324)
13 Skills, 25 Skill Books for all skills (24 for Barter). Reading these books will increase the corresponding skill by 1, and even by 2 with Comprehension. That makes these Skill Books quite worth the effort.
A Ghoul Scientist called Murphy can be found in Northwest Seneca Station. He needs Sugar Bombs to complete an experiment he's doing on the Jet chem. Give him some and he'll turn it into an Ultrajet!