Is it better to use items such as Protein and Iron on your Pokemon when they are at a lower level or does it make no difference? I have noticed that when I use those items on a Pokemon at level 100 I only use a few before it says "It won't have any effect" meaning that the associated stat is maxed out, Whereas when I use those items on a lower level Pokemon I can use about ten. This is with level 50 Pokemon. So is it better to use items such as Protein and Iron on your Pokemon when they are at a low level or a high level or does it not matter?
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In Generation 1 and 2 games, it doesn't matter. Eventually, the amount of EV gain from those drugs is not really going to matter overall with your Pokemon's stats.
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