10 Focused MindDefeat a Doorkeeper without taking any damage.
10 OCDUse every weapon at least once in any level of the game in Story mode.
15 Aversion TherapyComplete a level on any difficulty without dying.
15 DraconistKill 400 Enemies while using the Dragon's Grasp.
15 Free AssociationKill 3 or more opponents at the same time in a Multiplayer game.
15 FreezerKill 400 Enemies while using the Hailstorm.
15 Heavy OperatorKill 400 Enemies while using the Minigun.
15 Manic EpisodeEnter Berserker Rage at least once in each level of the game in Story mode.
15 PaladinKill 400 Enemies while using the Sunbeam.
15 Poor SleeperComplete Story mode on the Bad Dream difficulty.
15 PsychoanalysisKill 25 opponents in any Multiplayer game mode.
15 StormerKill 400 Enemies while using Shock Therapy.
15 TechnicianKill 400 Enemies while using the Dream Cleaner.
15 WisdomFind and enter in all of the Secret areas in any one level of the game.
15 XenophobiaKill 10 or more enemies at the same time with any weapon.
20 DreamkillerDefeat a Dreamkiller without taking any damage.
20 MasterComplete Chapter 4 on any difficulty.
20 OperativeComplete Chapter 2 on any difficulty.
20 PractitionerComplete Chapter 1 on any difficulty.
20 SpecialistComplete Chapter 3 on any difficulty.
25 Absolute ThresholdAchieve the Gold weapon upgrade rank on the Insanity difficulty.
25 AstraphobiaComplete one level in Story mode while only using Shock Therapy.
25 Delusions of GrandeurFinish a Deathmatch game with the highest score (with at least 3 other players involved).
25 HeliophobiaComplete one level in Story mode while only using the Sunbeam.
25 HoplophobiaComplete one level in Story mode while only using the Minigun.
25 Instinctual ActionEnter Berserker Rage during a Multiplayer game.
25 Latent AbilitiesComplete every level on any difficulty without dying in the Subconscious.
25 LigyrophobiaComplete one level in Story mode while only using the Dream Cleaner.
25 MastermindConquer 50 brains in Conquest mode.
25 Mind GuardReturn your team's flag at least 5 times in one CTF match.
25 OpiophobiaComplete one level without receiving any Health pickups.
25 PagophobiaComplete one level in Story mode while only using the Hailstorm.
25 Psycho LogicalComplete a Single Player game in Time Trial mode.
25 RhabdophobiaComplete one level in Story mode while only using the Dragon's Grasp.
25 Simple JackComplete a Single Player game in Single Weapon mode.
25 SomnambulistComplete Story mode on the Nightmare difficulty.
30 PrescriptionKill 100 opponents in any Multiplayer game mode.
30 UntouchableKill 10 opponents in a row without dying in a Multiplayer game.
45 Lucid GuardianComplete Story mode on the Insanity difficulty.
5 BomberKill 100 Enemies while using the Dream Cleaner.
5 BreakerKill 100 Enemies while using the Hailstorm.
5 ConjurerKill 100 Enemies while using the Dragon's Grasp.
5 GunnerKill 100 Enemies while using the Minigun.
5 LighterKill 100 Enemies while using the Sunbeam.
5 ShockerKill 100 Enemies while using Shock Therapy.
50 TreatmentKill 300 opponents in any Multiplayer game mode.
75 ImmortalComplete every level on any difficulty without dying.