10 A Comfortable PaceClear mission 11 in Human Mode.
10 Easy Does ItClear all missions in Human Mode.
10 Half Way ThereClear mission 11 in Devil Hunter Mode.
10 Rock and a Hard PlaceClear Mission 11 in Son of Sparda Mode
10 Easier Said Than DoneClear Mission 11 in Dante Must Die Mode
10 Step into the LightClear All Missions in Heaven or Hell Mode
10 Tonight, We Dine in HellClear All Missions in Hell or Hell Mode
10 Nothing Left UnsaidClear all Secret Missions
10 The First CircleComplete Stage 10 of the Bloody Palace
10 The Second CircleClear stage 20 of Bloody Palace Mode
10 The Third CircleClear stage 30 of Bloody Palace Mode
10 The Fourth CircleClear stage 40 of Bloody Palace Mode
10 The Fifth CircleClear stage 50 of Bloody Palace Mode
10 The Sixth CircleClear stage 60 of Bloody Palace Mode
10 The Seventh CircleClear stage 70 of Bloody Palace Mode
10 The Eight CircleClear stage 80 of Bloody Palace Mode
10 The Ninth CircleClear stage 90 of Bloody Palace Mode
10 Smokin'!Complete a Stylish Rank S (Smokin'!) combo.
10 Smokin' Style!!Complete a Stylish Rank SS (Smokin' Style!!) combo.
10 Smokin' Sick Style!!!Complete a Stylish Rank SSS (Smokin' Sick Style!!!) combo.
10 Simply SpectacularComplete a mission with an S ranking.
10 Modus VivendiExtend the Vitality Gauge to maximum capacity
10 Bat Out of HellExtend the Devil Trigger Gauge to maximum capacity
10 River of RedAcquire 10,000 Red Orbs.
10 Filled with PrideAcquire 10,000 Proud Souls.
10 Rookie Devil HunterDefeat a total of 100 enemies.
20 Done and DoneClear all missions in Devil Hunter Mode.
20 The Best of the RestClear all missions in Human Mode with an S ranking.
20 Speak of the DevilClear the game with Super Nero (Dante)
20 Your Cup Runeth OverAcquire 100,000 Red Orbs.
20 Brimming with PrideAcquire 100,000 Proud Souls.
30 Hardly A Simple TaskClear All Missions in Son of Sparda Mode
30 A Cut AboveClear all missions in Devil Hunter Mode with an S ranking.
30 Skilled Devil HunterDefeat a total of 1,000 enemies.
40 All Bow Before YouClear All Missions in Dante Must Die Mode
40 A Stunning FeatClear all Missions in Son of Sparda Mode with an S Ranking
40 Covered in BloodClear All Bloody Palace Mode stages
40 Red Orb MillionaireAcquire 1,000,000 Red Orbs.
40 Proud MillionaireAcquire 1,000,000 Proud Souls.
50 Never Say DieClear all Missions in Dante Must Die Mode with an S Ranking
50 A Throne of GloryClear all Game Modes
50 King of the PalaceClear All Bloody Palace stages with an S Ranking
50 Legendary Devil HunterDefeat a total of 10,000 enemies.
50 Item CollectorAcquire a maximum number of all items
50 Skill Collector - NeroAcquire all of Nero's skills
50 Skill Collector - DanteAcquire all of Dante's skills